⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5463872 | 0.85 | ALDH1A1 (0.43) | — | |
| SCHEMBL10570523 | 0.76 | TLR4 (0.50) | — | |
| SCHEMBL6558335 | 0.75 | ALDH1A1 (0.45) | — | |
| SCHEMBL7039183 | 0.74 | RELA (0.50) | — | |
| SCHEMBL5410674 | 0.72 | TRPA1 (0.39) | — | |
| SCHEMBL7325160 | 0.72 | TRPA1 (0.39) | — | |
| SCHEMBL7039449 | 0.72 | TP53 (0.56) | — | |
| SCHEMBL14681134 | 0.72 | TRPA1 (0.54) | — | |
| SCHEMBL7039143 | 0.72 | NFE2L2 (0.52) | — | |
| SCHEMBL1399923 | 0.72 | TRPA1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 21962 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290431-A | Cycloguava compound based on pyrrolopyrrolidone and preparation method thereof | 北京理工大学 | 2024-07-05 | — | — | CN | claimed |
| CN-118290354-A | Preparation method of 1, 4-disubstituted triazole | 大连理工大学 | 2024-07-05 | — | — | CN | claimed |
| CN-112574123-B | JNK inhibitors, pharmaceutical compositions and uses thereof | 武汉朗来科技发展有限公司 | 2024-06-11 | — | — | CN | claimed |
| EP-4370206-A1 | ESTERS OF 7-COOH CBD DERIVATIVES AND THEIR USE AS PREVENTION, PROPHYLAXIS OF PROGRESSION, AND/OR TREATMENT OF NEUROGENERATIVE DISEASES | Receptorpharma Inc S-Corp (US) | 2024-05-22 | — | — | EP | claimed |
| EP-4367088-A1 | STRAINED BI-FUNCTIONALIZED TRANS-CYCLOOCTENES | Stichting Radboud Universiteit (NL) | 2024-05-15 | — | — | EP | claimed |
| EP-4355728-A1 | FRAGRANCE COMPOUNDS | Givaudan SA (CH) | 2024-04-24 | — | — | EP | claimed |
| CN-111278816-B | Dihydro quinolinones | C4医药公司 | 2024-03-15 | — | — | CN | claimed |
| CN-115135694-B | Polymeric excipients for drug delivery applications | 廷德尔配方服务有限责任公司 | 2024-03-15 | — | — | CN | claimed |
| CN-117677381-A | Fragrance composition | 科蒂公司 | 2024-03-08 | — | — | CN | claimed |
| EP-4087543-B1 | POLYMER EXCIPIENTS FOR DRUG DELIVERY APPLICATIONS | TYNDALL FORMULATION SERVICES LLC (US) | 2024-03-06 | — | — | EP | claimed |
| US-3954744-A | ANTIBACTERIAL | E. R. SQUIBB & SONS, INC. (US) | 1976-05-04 | — | — | US | claimed |
| US-3953436-A | 3,4-Dicarboxycephalosporins and derivatives | ELI LILLY AND COMPANY (US) | 1976-04-27 | — | — | US | claimed |
| US-3950347-A | NAPHTHOLACTAM DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | claimed |
| US-3948903-A | Substituted N-(1,2-dihydro-2-oxonicotinyl)-cephalexins and -cephaloglycins | PARKE, DAVIS & COMPANY (US) | 1976-04-06 | — | — | US | claimed |
| US-3949083-A | DIURETICS, SALURETICS, HYPERTENSION | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-06 | — | — | US | claimed |
| US-3944545-A | Process for preparing desacetoxycephalosporins | ELI LILLY AND COMPANY (US) | 1976-03-16 | — | — | US | claimed |
| US-3940395-A | CNS DEPRESSANT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-02-24 | — | — | US | claimed |
| US-3936447-A | 7-Acylamino-desacetoxy-cephalosporanic acid esters and their production | BAYER AKTIENGESELLSCHAFT (DT) | 1976-02-03 | — | — | US | claimed |
| US-3935198-A | BY HEATING THE PENICILLIN SULFOXIDE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1976-01-27 | — | — | US | claimed |
| US-3933784-A | Des-(ser13)-srif and intermediates | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-01-20 | — | — | US | claimed |