Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.64 |
| ▸ | HTR1A | P08908 | 2/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.64 |
| ▸ | HTR2A | P28223 | 2/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.64 |
| ▸ | DRD3 | P35462 | 2/20 | 0.64 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.58 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29364904 | 1.00 | DRD2 (0.64) | DRD2HTR1AADRA2AHTR2ASLC6A4 | |
| Hydrochloric Acid SCHEMBL2995613 | 0.99 | DRD2 (0.62) | DRD2HTR1AADRA2AHTR2ASLC6A4 | |
| Bromide SCHEMBL11205803 | 0.99 | DRD2 (0.62) | DRD2HTR1AADRA2AHTR2ASLC6A4 | |
| SCHEMBL26666399 | 0.91 | DRD2 (0.70) | DRD2HTR1AADRA2AHTR2ASLC6A4 | |
| SCHEMBL31286016 | 0.89 | OPRM1 (0.59) | DRD2HTR1AADRA2AHTR2ASLC6A4 | |
| SCHEMBL4222708 | 0.89 | OPRM1 (0.59) | DRD2HTR1AADRA2AHTR2ASLC6A4 | |
| Hydrochloric Acid SCHEMBL4635771 | 0.87 | OPRM1 (0.58) | DRD2HTR1AADRA2AHTR2ASLC6A4 | |
| SCHEMBL7177017 | 0.84 | DRD2 (0.62) | DRD2HTR1AADRA2AHTR2ASLC6A4 | |
| SCHEMBL7177015 | 0.84 | DRD2 (0.62) | DRD2HTR1AADRA2AHTR2ASLC6A4 | |
| Hydrochloric Acid SCHEMBL16989757 | 0.83 | DRD2 (0.61) | DRD2HTR1AADRA2AHTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240091199-A1 | Deuterated Domperidone Compositions, Methods, and Preparation | CINDOME PHARMA, INC. (US) | 2024-03-21 | — | — | US | claimed |
| CN-113995755-A | Deuterated domperidone composition and method for treating disorders | 辛多美制药有限公司 | 2022-02-01 | — | — | CN | claimed |
| US-20210137892-A1 | Deuterated Domperidone Compositions, Methods, and Preparation | CINRX PHARMA, LLC (US) | 2021-05-13 | — | — | US | claimed |
| EP-3644995-A1 | DEUTERATED DOMPERIDONE COMPOSITIONS, METHODS, AND PREPARATION | CinDome Pharma, Inc. (US) | 2020-05-06 | — | — | EP | claimed |
| CN-111093653-A | Deuterated domperidone composition, method and preparation | 辛多美制药有限公司 | 2020-05-01 | — | — | CN | claimed |
| WO-2019006078-A1 | DEUTERATED DOMPERIDONE COMPOSITIONS, METHODS, AND PREPARATION | CINRX PHARMA, LLC (US) | 2019-01-03 | — | — | WO | claimed |
| EP-3411031-A1 | DEUTERATED DOMPERIDONE COMPOSITIONS AND METHODS FOR THERAPY OF DISORDERS | Cinrx Pharma, LLC (US) | 2018-12-12 | — | — | EP | claimed |
| US-20170298046-A1 | DEUTERATED DOMPERIDONE COMPOSITIONS, METHODS, AND PREPARATION | CINDOME PHARMA, INC. | 2017-10-19 | — | — | US | claimed |
| WO-2017136617-A1 | DEUTERATED DOMPERIDONE COMPOSITIONS AND METHODS FOR THERAPY OF DISORDERS | CINRX PHARMA, LLC (US) | 2017-08-10 | — | — | WO | claimed |
| US-12478612-B2 | Deuterated domperidone compositions, methods, and preparation | CINDOME PHARMA, INC. (US) | 2025-11-25 | — | — | US | disclosed |
| US-12338226-B2 | Substituted benzodiazoles and use thereof in therapy | THOMAS HELLEDAYS STIFTELSE FOR MEDICINSK FORSKNING (SE) | 2025-06-24 | — | — | US | disclosed |
| CN-115754066-B | Method for detecting related substances in domperidone tablet | 佛山手心制药有限公司 | 2025-02-18 | — | — | CN | disclosed |
| US-20240287020-A1 | SUBSTITUTED BENZODIAZOLES AND USE THEREOF IN THERAPY | THOMAS HELLEDAYS STIFTELSE FÖR MEDICINSK FORSKNING (SE) | 2024-08-29 | — | — | US | disclosed |
| US-11970474-B2 | Substituted benzodiazoles and use thereof in therapy | THOMAS HELLEDAYS STIFTELSE FÖR MEDICINSK FORSKNING (SE) | 2024-04-30 | — | — | US | disclosed |
| US-4110333-A | ANTIEMETIC INTERMEDIATES | JANSSEN PHARMACEUTICA N.V. (BE) | 1978-08-29 | — | — | US | disclosed |
| US-4082755-A | NEUROLEPTIC | JANSSEN PHARMACEUTICA N.V. (BE) | 1978-04-04 | — | — | US | disclosed |
| US-4076821-A | 4,4-Diphenylcycloalkylpiperidines and psychotropic compositions thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JA) | 1978-02-28 | — | — | US | disclosed |
| US-4066772-A | ANTIEMETICS | JANSSEN PHARMACEUTICA N.V. (BE) | 1978-01-03 | — | — | US | disclosed |
| US-4031226-A | ANTIEMETIC, PSYCHOTROPIC | JANSSEN PHARMACEUTICA N.V. (BE) | 1977-06-21 | — | — | US | disclosed |
| US-3989707-A | NEUROLEPTIC AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240091199-A1 | Deuterated Domperidone Compositions, Methods, and Preparation | DRD2, DRD1, DRD4 | DRD2 1/4885HTR1A 24/4885ADRA2A 310/4885 |
| US-11970474-B2 | Substituted benzodiazoles and use thereof in therapy | XDH, CYP4X1, CYP11B2 | DRD2 1388/4885HTR1A 1609/4885ADRA2A 1485/4885 |
| US-20240287020-A1 | SUBSTITUTED BENZODIAZOLES AND USE THEREOF IN THERAPY | XDH, CYP11B2, CYP4X1 | DRD2 1221/4885HTR1A 1091/4885ADRA2A 1016/4885 |
| US-20170298046-A1 | DEUTERATED DOMPERIDONE COMPOSITIONS, METHODS, AND PREPARATION | DRD2, DRD1, DRD4 | DRD2 1/4885HTR1A 24/4885ADRA2A 310/4885 |
| US-20210137892-A1 | Deuterated Domperidone Compositions, Methods, and Preparation | DRD2, DRD1, DRD4 | DRD2 1/4885HTR1A 24/4885ADRA2A 310/4885 |
| US-12478612-B2 | Deuterated domperidone compositions, methods, and preparation | DRD2, DRD1, DRD4 | DRD2 1/4885HTR1A 24/4885ADRA2A 310/4885 |
| US-12338226-B2 | Substituted benzodiazoles and use thereof in therapy | XDH, CYP11B2, CYP4X1 | DRD2 1221/4885HTR1A 1091/4885ADRA2A 1016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.