Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.42 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.42 |
| ▸ | USP10 | Q14694 | 1/20 | 0.42 |
| ▸ | USP7 | Q93009 | 1/20 | 0.42 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2061399 | 0.90 | ATM (0.58) | PDE7ATDP1ATMTXNRD1TXNRD3 | |
| SCHEMBL10651245 | 0.84 | ALDH1A1 (0.56) | PDE7ATDP1ATMUSP10USP7 | |
| SCHEMBL282648 | 0.81 | TSHR (0.56) | TDP1TXNRD1TXNRD3TXNRD2ALDH1A1 | |
| SCHEMBL3874156 | 0.81 | PDE7A (0.58) | PDE7ATDP1ATMTXNRD1TXNRD3 | |
| SCHEMBL6556635 | 0.80 | PDE7A (0.57) | PDE7AUSP7ALDH1A1KMT2APDE4B | |
| SCHEMBL11432656 | 0.80 | ALDH1A1 (0.54) | PDE7ATDP1TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL1026140 | 0.80 | TXNRD1 (0.42) | PDE7ATXNRD1TXNRD3TXNRD2ALDH1A1 | |
| SCHEMBL10651192 | 0.78 | MAPT (0.49) | PDE7ATDP1ATMUSP10USP7 | |
| SCHEMBL14866332 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KMT2AHTTMAPTMAPK1 | |
| SCHEMBL5913415 | 0.78 | ALDH1A1 (0.57) | TDP1TXNRD1TXNRD3TXNRD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976725-B1 | Process for the continuous preparation of amino-halogenophenyl alkyl thioethers | BAYER CHEMICALS AG (DE) | 2004-03-03 | — | — | EP | claimed |
| US-6077974-A | Process for the continuous preparation of amino-halo-genophenyl alkyl thioethers | BAYER AKTIENGESELLSCHAFT (DE) | 2000-06-20 | — | — | US | claimed |
| EP-0976725-A2 | Process for the continuous preparation of amino-halogenophenyl alkyl thioethers | Bayer Aktiengesellschaft (DE) | 2000-02-02 | — | — | EP | claimed |
| US-20180111905-A1 | N2-(2-METHOXYPHENYL)PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR CANCER PREVENTION OR TREATMENT CONTAINING SAME AS ACTIVE INGREDIENT | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2018-04-26 | — | — | US | disclosed |
| EP-0976725-B1 | Process for the continuous preparation of amino-halogenophenyl alkyl thioethers | BAYER CHEMICALS AG (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6077974-A | Process for the continuous preparation of amino-halo-genophenyl alkyl thioethers | BAYER AKTIENGESELLSCHAFT (DE) | 2000-06-20 | — | — | US | disclosed |
| EP-0976725-A2 | Process for the continuous preparation of amino-halogenophenyl alkyl thioethers | Bayer Aktiengesellschaft (DE) | 2000-02-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180111905-A1 | N2-(2-METHOXYPHENYL)PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR CANCER PREVENTION OR TREATMENT CONTAINING SAME AS ACTIVE INGREDIENT | ALK, NPM1, EML4 | PDE7A 4052/4885TDP1 1272/4885ATM 1285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.