Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 9/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558747 | 0.82 | BACE1 (0.42) | BACE1CTSDPSENENECE1OPRD1 | |
| SCHEMBL6558843 | 0.80 | BACE1 (0.38) | BACE1CTSDPSENENECE1OPRD1 | |
| SCHEMBL6558827 | 0.80 | ECE1 (0.30) | ECE1 | |
| SCHEMBL6559672 | 0.73 | GNPAT (0.37) | BACE1CTSDECE1 | |
| SCHEMBL6558480 | 0.72 | BACE1 (0.37) | BACE1CTSDPSENENECE1 | |
| SCHEMBL6558875 | 0.72 | CASP1 (0.42) | BACE1CTSDPSENENOPRD1 | |
| SCHEMBL6558450 | 0.71 | MAGI3 (0.37) | BACE1CTSDPSENEN | |
| SCHEMBL6558510 | 0.71 | TASP1 (0.31) | — | |
| SCHEMBL6558448 | 0.69 | PSENEN (0.39) | CTSDPSENEN | |
| SCHEMBL6558839 | 0.69 | PSENEN (0.36) | BACE1CTSDPSENENOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948523-B1 | PEPTIDOMIMETIC INHIBITORS OF THE HUMAN CYTOMEGALOVIRUS PROTEASE | BOEHRINGER INGELHEIM CA LTD (CA) | 2004-03-17 | — | — | EP | claimed |
| EP-0948523-A1 | PEPTIDOMIMETIC INHIBITORS OF THE HUMAN CYTOMEGALOVIRUS PROTEASE | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 1999-10-13 | — | — | EP | claimed |
| WO-1998029435-A1 | PEPTIDOMIMETIC INHIBITORS OF THE HUMAN CYTOMEGALOVIRUS PROTEASE | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 1998-07-09 | — | — | WO | claimed |
| EP-0948523-B1 | PEPTIDOMIMETIC INHIBITORS OF THE HUMAN CYTOMEGALOVIRUS PROTEASE | BOEHRINGER INGELHEIM CA LTD (CA) | 2004-03-17 | — | — | EP | disclosed |
| US-6291640-B1 | OLIGOPEPTIDES; SOLID PHASE SYNTHESIS | BOEHRINGER INGELHEIM LTD. (CA) | 2001-09-18 | — | — | US | disclosed |