Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.45 |
| ▸ | GAA | P10253 | 10/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | GLA | P06280 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.43 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558676 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL7467918 | 0.87 | ALDH1A1 (0.50) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL7467920 | 0.87 | ALDH1A1 (0.50) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL6560822 | 0.83 | KDM4E (0.62) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL6559505 | 0.78 | KDM4E (0.61) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL6559504 | 0.78 | KDM4E (0.61) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL6603109 | 0.77 | MAOB (0.60) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL6603113 | 0.77 | MAOB (0.60) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL6938486 | 0.73 | KCNE1 (0.57) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL6561065 | 0.73 | MAPT (0.43) | KDM4EALDH1A1GAAHPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807629-B1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |