Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559262 | 0.88 | TRPV1 (0.43) | KCNA5SIRT2TRPV1RAB9ANPC1 | |
| SCHEMBL6559931 | 0.86 | KCNA5 (0.44) | HPGDKCNA5SIRT2TRPV1RAB9A | |
| SCHEMBL6561146 | 0.85 | KCNA5 (0.41) | KCNA5SIRT2TRPV1RAB9ANPC1 | |
| SCHEMBL6558681 | 0.81 | KCNA5 (0.42) | HPGDKCNA5SIRT2TRPV1RAB9A | |
| SCHEMBL6560815 | 0.81 | TRPV1 (0.48) | TRPV1CYP3A4 | |
| SCHEMBL6559569 | 0.80 | RAB9A (0.37) | HPGDKCNA5SIRT2RAB9ANPC1 | |
| SCHEMBL6559277 | 0.79 | KCNE1 (0.40) | HPGDRAB9ANPC1SMN1; SMN2ALOX5 | |
| SCHEMBL6559751 | 0.79 | TRPV1 (0.43) | TRPV1ALDH1A1 | |
| SCHEMBL6560813 | 0.77 | KCNE1 (0.42) | HPGDKCNA5RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6559826 | 0.77 | SMN1; SMN2 (0.36) | HPGDKCNA5SIRT2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807629-B1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |