Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559277 | 0.90 | KCNE1 (0.40) | RAB9ASMN1; SMN2NPC1HPGDALOX5 | |
| SCHEMBL6559550 | 0.89 | MEN1 (0.37) | ALDH1A1MEN1KMT2AMAPK1KCNA5 | |
| SCHEMBL6560813 | 0.88 | KCNE1 (0.42) | RAB9ASMN1; SMN2NPC1HPGDALDH1A1 | |
| SCHEMBL6559826 | 0.87 | SMN1; SMN2 (0.36) | RAB9ASMN1; SMN2NPC1HPGDALOX5 | |
| SCHEMBL6558778 | 0.87 | HTR1A (0.36) | RAB9ASMN1; SMN2NPC1CASP3SENP7 | |
| SCHEMBL6559333 | 0.84 | KCNE1 (0.44) | HPGDALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6559205 | 0.82 | SMN1; SMN2 (0.38) | RAB9ASMN1; SMN2NPC1HPGDALOX5 | |
| SCHEMBL6558679 | 0.80 | HPGD (0.41) | RAB9ASMN1; SMN2NPC1HPGDALOX5 | |
| SCHEMBL6560975 | 0.79 | KCNE1 (0.47) | — | |
| SCHEMBL6559604 | 0.79 | MEN1 (0.36) | RAB9ASMN1; SMN2NPC1HPGDALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807629-B1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |