⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560006 | 0.81 | — | — | |
| SCHEMBL477281 | 0.68 | ALDH1A1 (0.33) | — | |
| SCHEMBL28153641 | 0.67 | HPGD (0.37) | — | |
| SCHEMBL2815518 | 0.66 | ALDH1A1 (0.36) | — | |
| SCHEMBL28207782 | 0.61 | LMNA (0.37) | — | |
| SCHEMBL1785410 | 0.61 | MAPT (0.32) | — | |
| SCHEMBL6558731 | 0.61 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL3691610 | 0.60 | CHRM2 (0.31) | — | |
| SCHEMBL8164117 | 0.59 | — | — | |
| SCHEMBL909008 | 0.59 | MITF (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0926164-B1 | Substituted amino silane compounds and catalyst for the polymerization of alpha-olefins containing them | BASELL NORTH AMERICA INC (US) | 2004-02-25 | — | — | EP | disclosed |
| US-6130180-A | Catalyst for the polymerization of alpha-olefins containing substituted amino silane compounds | MONTELL NORTH AMERICA INC. (US) | 2000-10-10 | — | — | US | disclosed |
| EP-0926164-A2 | Substituted amino silane compounds and catalyst for the polymerization of alpha-olefins containing them | MONTELL NORTH AMERICA INC. (US) | 1999-06-30 | — | — | EP | disclosed |