SCHEMBL6558790

SCHEMBL6558790

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nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CTSD P07339 2/20 0.35
PGA5 P0DJD9 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6559645 0.84 ALDH1A1 (0.40) CTSD
SCHEMBL6558448 0.73 PSENEN (0.39) CTSD
SCHEMBL6559665 0.71 PSENEN (0.43) CTSD
SCHEMBL6558875 0.71 CASP1 (0.42) CTSD
SCHEMBL6558747 0.70 BACE1 (0.42) CTSD
SCHEMBL6558811 0.70 FURIN (0.46)
SCHEMBL6558843 0.70 BACE1 (0.38) CTSD
SCHEMBL6560709 0.69 PSENEN (0.41) CTSD
SCHEMBL6558465 0.69 PSENEN (0.41) CTSD
SCHEMBL6558450 0.68 MAGI3 (0.37) CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0948523-B1 PEPTIDOMIMETIC INHIBITORS OF THE HUMAN CYTOMEGALOVIRUS PROTEASE BOEHRINGER INGELHEIM CA LTD (CA) 2004-03-17 EP disclosed