Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTRA1 | Q92743 | 10/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | GNPAT | O15228 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23600925 | 0.84 | ACE (0.55) | BACE1GNPATCTSSCTSK | |
| SCHEMBL23572632 | 0.84 | ACE (0.55) | BACE1GNPATCTSSCTSK | |
| SCHEMBL23572631 | 0.84 | ACE (0.55) | BACE1GNPATCTSSCTSK | |
| SCHEMBL7270319 | 0.82 | CTSS (0.52) | GNPATCTSSCTSK | |
| SCHEMBL6558875 | 0.81 | CASP1 (0.42) | BACE1GNPAT | |
| SCHEMBL6558448 | 0.81 | PSENEN (0.39) | HTRA1 | |
| SCHEMBL29112224 | 0.81 | MME (0.58) | BACE1GNPAT | |
| SCHEMBL6559665 | 0.80 | PSENEN (0.43) | — | |
| SCHEMBL6559645 | 0.80 | ALDH1A1 (0.40) | — | |
| SCHEMBL23600939 | 0.80 | CTSD (0.55) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948523-B1 | PEPTIDOMIMETIC INHIBITORS OF THE HUMAN CYTOMEGALOVIRUS PROTEASE | BOEHRINGER INGELHEIM CA LTD (CA) | 2004-03-17 | — | — | EP | claimed |
| US-6291640-B1 | OLIGOPEPTIDES; SOLID PHASE SYNTHESIS | BOEHRINGER INGELHEIM LTD. (CA) | 2001-09-18 | — | — | US | claimed |
| EP-0948523-B1 | PEPTIDOMIMETIC INHIBITORS OF THE HUMAN CYTOMEGALOVIRUS PROTEASE | BOEHRINGER INGELHEIM CA LTD (CA) | 2004-03-17 | — | — | EP | disclosed |
| US-6291640-B1 | OLIGOPEPTIDES; SOLID PHASE SYNTHESIS | BOEHRINGER INGELHEIM LTD. (CA) | 2001-09-18 | — | — | US | disclosed |