SCHEMBL6559243

SCHEMBL6559243

CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CO)[C@@H](O)[C@@H](O)[C@H](O)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CTSK P43235 12/20 0.62
PSMB1 P20618 1/20 0.62
CTSL P07711 6/20 0.59
CTSB P07858 5/20 0.59
CTSS P25774 3/20 0.59
CAPN1 P07384 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1841693 0.87 CTSK (0.70) CTSKPSMB1CTSLCTSBCTSS
SCHEMBL8951282 0.86 CAPN1 (0.66) CTSKPSMB1CTSLCTSBCTSS
SCHEMBL6558995 0.86 PSMB1 (0.56) CTSKPSMB1CTSLCTSBCTSS
SCHEMBL6444976 0.86 CTSK (0.72) CTSKPSMB1CTSLCTSBCTSS
SCHEMBL6560880 0.85 PSMB1 (0.64) CTSKPSMB1CTSLCTSBCTSS
SCHEMBL8971578 0.84 CTSK (0.67) CTSKPSMB1CTSLCTSBCTSS
SCHEMBL7921828 0.82 CTSK (0.73) CTSKCTSLCTSBCTSSCAPN1
SCHEMBL25406813 0.82 CTSK (0.77) CTSKCTSLCTSBCTSSCAPN1
SCHEMBL8823918 0.82 CTSK (0.77) CTSKCTSLCTSBCTSSCAPN1
SCHEMBL20770085 0.82 CTSK (0.77) CTSKCTSLCTSBCTSSCAPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0998488-B1 POLYOL-AMINO ACID COMPOUNDS HAVING ANTI-HELICOBACTER PYLORI ACTIVITY TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2004-03-17 EP disclosed
US-6423869-B1 BACTERICIDES, ANTIULCER AGENTS TAKEDA CHEMICAL INDUSTRIES, INC. (JP) 2002-07-23 US disclosed