Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 1/20 | 0.64 |
| ▸ | CTSK | P43235 | 10/20 | 0.52 |
| ▸ | CTSL | P07711 | 5/20 | 0.49 |
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | CTSB | P07858 | 3/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558995 | 0.93 | PSMB1 (0.56) | PSMB1CTSKCTSLCTSSCTSB | |
| SCHEMBL6560838 | 0.88 | CTSK (0.52) | PSMB1CTSKCTSLCTSSCTSB | |
| SCHEMBL6559234 | 0.87 | CTSK (0.50) | PSMB1CTSKCTSLCTSSCTSB | |
| SCHEMBL6558612 | 0.85 | PSMB1 (0.50) | PSMB1CTSKCTSLCTSSCTSB | |
| SCHEMBL6559243 | 0.85 | CTSK (0.62) | PSMB1CTSKCTSLCTSSCTSB | |
| SCHEMBL6560489 | 0.82 | METAP2 (0.47) | PSMB1 | |
| SCHEMBL6558906 | 0.82 | PSMB1 (0.43) | PSMB1 | |
| SCHEMBL6558606 | 0.81 | PSMB1 (0.43) | PSMB1CTSKCTSLCTSS | |
| SCHEMBL6559351 | 0.79 | METAP2 (0.45) | PSMB1 | |
| SCHEMBL6558570 | 0.79 | BACE1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998488-B1 | POLYOL-AMINO ACID COMPOUNDS HAVING ANTI-HELICOBACTER PYLORI ACTIVITY | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-03-17 | — | — | EP | disclosed |
| US-6423869-B1 | BACTERICIDES, ANTIULCER AGENTS | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 2002-07-23 | — | — | US | disclosed |