SCHEMBL6560015

SCHEMBL6560015

CC(C)(C)N(C(=O)O)N1CCCC1[Si](C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6558727 0.95
SCHEMBL6559973 0.80 PEPD (0.30)
SCHEMBL6560006 0.77
SCHEMBL6535156 0.77 LMNA (0.43) LMNA
SCHEMBL28207782 0.66 LMNA (0.37) LMNA
SCHEMBL477281 0.65 ALDH1A1 (0.33)
SCHEMBL3691610 0.65 CHRM2 (0.31)
SCHEMBL2815518 0.64 ALDH1A1 (0.36)
SCHEMBL3690670 0.62 CYP2D6 (0.33) LMNA
SCHEMBL28153641 0.61 HPGD (0.37) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0926164-B1 Substituted amino silane compounds and catalyst for the polymerization of alpha-olefins containing them BASELL NORTH AMERICA INC (US) 2004-02-25 EP disclosed
US-6130180-A Catalyst for the polymerization of alpha-olefins containing substituted amino silane compounds MONTELL NORTH AMERICA INC. (US) 2000-10-10 US disclosed
EP-0926164-A2 Substituted amino silane compounds and catalyst for the polymerization of alpha-olefins containing them MONTELL NORTH AMERICA INC. (US) 1999-06-30 EP disclosed