Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560000 | 0.97 | PRMT5 (0.40) | RIPK1ALDH1A1ROCK2OPRK1CCKBR | |
| SCHEMBL22055802 | 0.76 | ALDH1A1 (0.48) | ALDH1A1ROCK2GAAMAPK1MAOB | |
| SCHEMBL878861 | 0.73 | NPSR1 (0.56) | RIPK1ALDH1A1ROCK2GAASCD5 | |
| SCHEMBL24775063 | 0.70 | DRD2 (0.46) | RIPK1ALDH1A1GAAMAOBMAOA | |
| SCHEMBL19501003 | 0.70 | RIPK1 (0.62) | RIPK1ROCK2ADAM17OPRK1SCD5 | |
| SCHEMBL19367188 | 0.70 | RIPK1 (0.50) | RIPK1 | |
| SCHEMBL24453925 | 0.70 | SMN1; SMN2 (0.37) | ALDH1A1LMNA | |
| SCHEMBL12677863 | 0.69 | ADAM17 (0.55) | RIPK1ALDH1A1ROCK2ADAM17SCD5 | |
| SCHEMBL6560855 | 0.69 | RIPK1 (0.49) | RIPK1ALDH1A1ROCK2ADAM17OPRK1 | |
| SCHEMBL28167683 | 0.69 | RIPK1 (0.58) | RIPK1OPRK1JAK2NTRK1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0926164-B1 | Substituted amino silane compounds and catalyst for the polymerization of alpha-olefins containing them | BASELL NORTH AMERICA INC (US) | 2004-02-25 | — | — | EP | disclosed |
| US-6130180-A | Catalyst for the polymerization of alpha-olefins containing substituted amino silane compounds | MONTELL NORTH AMERICA INC. (US) | 2000-10-10 | — | — | US | disclosed |
| EP-0926164-A2 | Substituted amino silane compounds and catalyst for the polymerization of alpha-olefins containing them | MONTELL NORTH AMERICA INC. (US) | 1999-06-30 | — | — | EP | disclosed |