Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27531822 | 0.86 | KDM4E (0.35) | ACHESIGMAR1BCHEMEN1KMT2A | |
| SCHEMBL13298011 | 0.82 | ACHE (0.44) | ACHESIGMAR1BCHEKDM5BMEN1 | |
| SCHEMBL25230992 | 0.80 | SIGMAR1 (0.46) | ACHESIGMAR1BCHEKDM5BMEN1 | |
| SCHEMBL5258395 | 0.80 | KDM4E (0.46) | ACHESIGMAR1BCHEKDM5BMEN1 | |
| SCHEMBL10310212 | 0.78 | MEN1 (0.36) | ACHESIGMAR1BCHEKDM5BMEN1 | |
| SCHEMBL5258391 | 0.78 | ACHE (0.42) | ACHESIGMAR1BCHEKDM5BMEN1 | |
| SCHEMBL27700415 | 0.78 | ALDH1A1 (0.37) | ACHESIGMAR1BCHEKDM5BMEN1 | |
| SCHEMBL4374960 | 0.78 | SIGMAR1 (0.39) | ACHESIGMAR1BCHEKDM5BMEN1 | |
| SCHEMBL10288810 | 0.77 | MEN1 (0.52) | ACHESIGMAR1BCHEKDM5BMEN1 | |
| SCHEMBL13298030 | 0.76 | ALDH1A1 (0.44) | ACHESIGMAR1BCHEKDM5BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101809209-B | Elastic polyurethane yarn and process for production thereof | OPELONTEX CO LTD | 2012-08-29 | — | — | CN | disclosed |
| CN-101321794-B | Fast curing aliphatic rim elastomers | BAYER MATERIALSCIENCE LLC | 2012-01-11 | — | — | CN | disclosed |
| CN-101321798-B | Weather resistant polyurethane elastomer | BAYER MATERIALSCIENCE LLC | 2011-09-21 | — | — | CN | disclosed |
| CN-101321792-B | Polyurethane elastomers comprising allophanate modified isocyanates | BAYER MATERIALSCIENCE LLC | 2011-04-13 | — | — | CN | disclosed |
| US-20100286126-A1 | Organic Compounds | NOVARTIS AG (CH) | 2010-11-11 | — | — | US | disclosed |
| CN-101809209-A | Elastic polyurethane yarn and process for production thereof | OPELONTEX CO LTD | 2010-08-18 | — | — | CN | disclosed |
| EP-1292604-B1 | 2-AMINOCARBONYL-9H-PURINE DERIVATIVES | PFIZER LTD (GB) | 2009-05-13 | — | — | EP | disclosed |
| CN-101410431-A | Polyurethane elastomers comprising allophanate modified isocyanates | BAYER MATERIALSCIENCE LLC (US) | 2009-04-15 | — | — | CN | disclosed |
| CN-101321798-A | Weather resistant polyurethane elastomer | BAYER MATERIALSCIENCE LLC (US) | 2008-12-10 | — | — | CN | disclosed |
| CN-101321792-A | Polyurethane elastomers comprising allophanate modified isocyanates | BAYER MATERIALSCIENCE LLC (US) | 2008-12-10 | — | — | CN | disclosed |
| CN-101321794-A | Fast curing aliphatic rim elastomers | BAYER MATERIALSCIENCE LLC (US) | 2008-12-10 | — | — | CN | disclosed |
| EP-1397140-A2 | COMBINATION OF AN ADENOSINE A2A-RECEPTOR AGONIST AND TIOTROPIUM OR A DERIVATIVE THEREOF FOR TREATING OBSTRUCTIVE AIRWAYS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-03-17 | — | — | EP | disclosed |
| EP-1395287-A1 | AN ADENOSINE A2A RECEPTOR AGONIST AND AN ANTICHOLINERGIC AGENT IN COMBINATION FOR TREATING OBSTRUCTIVE AIRWAYS DISEASES | PFIZER INC. (US) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002096462-A1 | AN ADENOSINE A2A RECEPTOR AGONIST AND AN ANTICHOLINERGIC AGENT IN COMBINATION FOR TREATING OBSTRUCTIVE AIRWAYS DISEASES | PFIZER INC. (US) | 2002-12-05 | — | — | WO | disclosed |
| WO-2002094273-A2 | COMBINATION OF AN ADENOSINE A2A-RECEPTOR AGONIST AND TIOTROPIUM OR A DERIVATIVE THEREOF FOR TREATING OBSTRUCTIVE AIRWAYS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286126-A1 | Organic Compounds | CYP3A43, SLCO1B3, CYP2C19 | ACHE 1626/4885SIGMAR1 134/4885BCHE 3026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.