Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 12/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 12/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560005 | 0.91 | KCNE1 (0.43) | KCNE1KCNQ1KCNH2TRPV1 | |
| SCHEMBL6558778 | 0.90 | HTR1A (0.36) | KCNE1KCNQ1HTR1AHTR1DHTR2C | |
| SCHEMBL6559388 | 0.89 | KCNE1 (0.43) | KCNE1KCNQ1HTR1AHTR1DHTR2C | |
| SCHEMBL6561170 | 0.88 | HTR1D (0.35) | KCNE1KCNQ1HTR1AHTR1DHTR2C | |
| SCHEMBL6559277 | 0.86 | KCNE1 (0.40) | KCNE1KCNQ1TSHRKCNH2 | |
| SCHEMBL6559208 | 0.84 | KCNE1 (0.46) | KCNE1KCNQ1HTR1AHTR1DHTR2C | |
| SCHEMBL6602008 | 0.83 | KCNE1 (0.44) | KCNE1KCNQ1KCNH2TRPV1 | |
| SCHEMBL6559550 | 0.80 | MEN1 (0.37) | KCNE1KCNQ1 | |
| SCHEMBL6558501 | 0.79 | KCNE1 (0.45) | KCNE1KCNQ1 | |
| SCHEMBL6559386 | 0.78 | KCNA5 (0.39) | KCNE1KCNQ1HTR1AHTR1DHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807629-B1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |