Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KCNE1 | P15382 | 6/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 6/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559550 | 0.91 | MEN1 (0.37) | KCNE1KCNQ1CYP2C9KCNA5 | |
| SCHEMBL6560808 | 0.90 | KCNE1 (0.41) | HTR1AHTR1DHTR2CTSHRKCNE1 | |
| SCHEMBL6559388 | 0.88 | KCNE1 (0.43) | HTR1AHTR1DHTR2CTSHRKCNE1 | |
| SCHEMBL6559569 | 0.87 | RAB9A (0.37) | TSHRNPC1RAB9ACASP3SMN1; SMN2 | |
| SCHEMBL6561170 | 0.87 | HTR1D (0.35) | HTR1AHTR1DHTR2CTSHRKCNE1 | |
| SCHEMBL6559208 | 0.83 | KCNE1 (0.46) | HTR1AHTR1DHTR2CTSHRKCNE1 | |
| SCHEMBL6560975 | 0.81 | KCNE1 (0.47) | KCNE1KCNQ1 | |
| SCHEMBL6560005 | 0.80 | KCNE1 (0.43) | KCNE1KCNQ1KCNA5 | |
| SCHEMBL6558501 | 0.78 | KCNE1 (0.45) | KCNE1KCNQ1KCNA5 | |
| SCHEMBL6559957 | 0.78 | KCNE1 (0.50) | KCNE1KCNQ1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807629-B1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |