Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 4/20 | 0.35 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558778 | 0.91 | HTR1A (0.36) | KCNE1KCNQ1KCNA5CYP2C9 | |
| SCHEMBL6560005 | 0.89 | KCNE1 (0.43) | MEN1KMT2ATDP1TBXA2RTBXAS1 | |
| SCHEMBL6559569 | 0.89 | RAB9A (0.37) | MEN1KMT2AALDH1A1MAPK1KCNA5 | |
| SCHEMBL6558501 | 0.87 | KCNE1 (0.45) | MEN1KMT2ATBXA2RTBXAS1KCNE1 | |
| SCHEMBL6559508 | 0.86 | MEN1 (0.35) | MEN1KMT2ATDP1TBXA2RTBXAS1 | |
| SCHEMBL6560975 | 0.83 | KCNE1 (0.47) | KCNE1KCNQ1AKR1B1 | |
| SCHEMBL6559607 | 0.82 | KCNE1 (0.47) | MEN1KMT2ATBXA2RTBXAS1KCNE1 | |
| SCHEMBL6559500 | 0.81 | NPSR1 (0.38) | MEN1KMT2ATDP1TBXA2RTBXAS1 | |
| SCHEMBL6560808 | 0.80 | KCNE1 (0.41) | KCNE1KCNQ1 | |
| SCHEMBL6559957 | 0.80 | KCNE1 (0.50) | MEN1KMT2AKCNE1KCNQ1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807629-B1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |