Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 3/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27554946 | 0.87 | PGR (0.38) | PGRRXRARXRBRXRGKDM4E | |
| SCHEMBL8597048 | 0.80 | ALDH1A1 (0.43) | PGRRXRARXRBRXRGKDM4E | |
| SCHEMBL24862660 | 0.75 | PGR (0.48) | PGRRXRARXRBRXRGKDM4E | |
| SCHEMBL568994 | 0.74 | PGR (0.55) | CA2PGRKDM4EALDH1A1 | |
| SCHEMBL6562466 | 0.73 | PGR (0.44) | PGRALDH1A1LMNAPOLBMAPK1 | |
| SCHEMBL6937210 | 0.73 | MAPT (0.54) | CA2PGRKDM4EALDH1A1LMNA | |
| SCHEMBL30353273 | 0.73 | PGR (0.44) | PGRALDH1A1LMNAPOLBMAPK1 | |
| SCHEMBL485022 | 0.72 | TDP2 (0.50) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL6561051 | 0.70 | CA2 (0.38) | CA2PGRKDM4EALDH1A1CYP26A1 | |
| SCHEMBL7565951 | 0.69 | PGR (0.44) | CA2PGRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1085009-B1 | INDAN DERIVATIVES | NISSAN CHEMICAL IND LTD (JP) | 2004-11-10 | — | — | EP | disclosed |
| US-6486178-B1 | Indane derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2002-11-26 | — | — | US | disclosed |
| EP-1085009-A1 | INDAN DERIVATIVES | Nissan Chemical Industries, Ltd. (JP) | 2001-03-21 | — | — | EP | disclosed |