Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.56 |
| ▸ | CA2 | P00918 | 10/20 | 0.56 |
| ▸ | CA7 | P43166 | 8/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 8/20 | 0.56 |
| ▸ | CA12 | O43570 | 7/20 | 0.56 |
| ▸ | CA9 | Q16790 | 6/20 | 0.56 |
| ▸ | GRM7 | Q14831 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561215 | 0.84 | GRM7 (0.60) | CA1CA2CA7CA14CA12 | |
| SCHEMBL6560917 | 0.81 | GAA (0.54) | CA1CA2CA7CA14CA12 | |
| SCHEMBL6559473 | 0.79 | CA1 (0.68) | CA1CA2CA7CA14CA12 | |
| SCHEMBL8008813 | 0.76 | CA1 (0.64) | CA1CA2CA7CA14CA12 | |
| SCHEMBL6583483 | 0.76 | CA1 (0.64) | CA1CA2CA7CA14CA12 | |
| SCHEMBL8887633 | 0.76 | HTR1D (0.57) | CA1CA2CA7CA14CA12 | |
| SCHEMBL11294282 | 0.75 | MTNR1A (0.64) | GRM7MME | |
| Hydrochloric Acid SCHEMBL11453887 | 0.75 | CA1 (0.62) | CA1CA2CA7CA14CA12 | |
| SCHEMBL4641731 | 0.74 | CA1 (0.47) | CA1CA2CA7CA14CA12 | |
| SCHEMBL8885912 | 0.74 | CA1 (0.40) | CA1CA2CA7CA14CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091946-B1 | NEW 2-AMINOTHIAZOL-FUSED 2-AMINOINDANS AND 2-AMINOTETRALINS AND THEIR USE | WIKSTROEM HAKAN VILHELM (NL) | 2004-03-17 | — | — | EP | disclosed |
| US-6291494-B1 | 2-aminothiazol-fused 2-aminoindans and 2-aminotetralins and their use | ASTRAZENECA AB (SE) | 2001-09-18 | — | — | US | disclosed |
| EP-1091946-A1 | NEW 2-AMINOTHIAZOL-FUSED 2-AMINOINDANS AND 2-AMINOTETRALINS AND THEIR USE | WIKSTRÖM, Hakan Vilhelm (NL) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001680-A1 | NEW 2-AMINOTHIAZOL-FUSED 2-AMINOINDANS AND 2-AMINOTETRALINS AND THEIR USE | WIKSTROEM HAKAN VILHELM (NL) | 2000-01-13 | — | — | WO | disclosed |