Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 4/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27633703 | 0.87 | KDM4E (0.44) | KIF11ALDH1A1MAPTCYP11B1CYP11B2 | |
| SCHEMBL10590631 | 0.85 | AR (0.54) | ALDH1A1CYP11B1CYP11B2ARKDM4E | |
| SCHEMBL3893100 | 0.85 | KDM4E (0.46) | ALDH1A1TDP1ARKDM4E | |
| SCHEMBL9390186 | 0.85 | AR (0.54) | KIF11AR | |
| SCHEMBL3890191 | 0.85 | PTGES (0.38) | KIF11CYP11B1CYP11B2AR | |
| SCHEMBL10590924 | 0.85 | KIF11 (0.47) | KIF11ALDH1A1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL9193868 | 0.85 | MAOA (0.45) | ALDH1A1MAPTSMN1; SMN2TDP1AR | |
| Bromide SCHEMBL29618239 | 0.84 | KDM4E (0.45) | ALDH1A1TDP1ARKDM4E | |
| SCHEMBL3893630 | 0.81 | AR (0.40) | ALDH1A1CYP11B2ARKDM4E | |
| SCHEMBL3896879 | 0.80 | KDM4E (0.35) | ALDH1A1CYP11B1CYP11B2ARKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035113-B1 | Process for the preparation of 2-aryl-5-(perfluoroalkyl)pyrrole compounds from N-[1-chloro-1-(perfluoroalkyl)methyl]arylimidoyl chloride compounds | BASF AG (DE) | 2004-10-06 | — | — | EP | disclosed |
| EP-0934929-B1 | Process for the preparation of 2-aryl-5-(perfluoroalkyl)pyrrole compounds from N-(arylmethylene)-1-chloro-1-(perfluoroalkyl) methylamine compounds | BASF AG (DE) | 2003-09-17 | — | — | EP | disclosed |
| US-6596902-B2 | Useful for insecticides and the control of acarid pests; chemical intermediates in the preparation of arylpyrrole compounds such as chlorfenapyr | BASF AKTIENGESELLSCHAFT (DE) | 2003-07-22 | — | — | US | disclosed |
| US-20020049338-A1 | Process for the preparation of 2-aryl-5- (perfluoro-alkyl) pyrrole compounds from N-[1-chloro-1-(perfluoroalkyl) methyl] arylimidoyl chloride compounds | AMERICAN CYANAMID COMPANY | 2002-04-25 | — | — | US | disclosed |
| US-6320059-B1 | REACTING N-(1-CHLORO-1-(PERFLUOROALKYL)METHYL)ARYLIMIDOYL CHLORIDE COMPOUND WITH DIENEOPHILE COMPOUND OR SUBSTITUTED HALOETHANE COMPOUND, AND BASE, IN PRESENCE OF SOLVENT | AMERICAN CYANAMID COMPANY | 2001-11-20 | — | — | US | disclosed |
| US-6133455-A | INSECTICIDAL AND ACARICIDAL AGENTS; PREPARED FROM N-(ARYLMETHYLENE)-1-CHLORO-1-(PERFLUOROALKYL) METHYLAMINE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 2000-10-17 | — | — | US | disclosed |
| CN-1267667-A | Process for producing 2-aryl-5-(perfluoroalkyl) pyrrole compound from N-[1-chlorine-1-(perfluoroalkyl) quadri group] imido aryl chlorine compound | AMERICAN CYANAMID CO (US) | 2000-09-27 | — | — | CN | disclosed |
| EP-1035113-A2 | Process for the preparation of 2-aryl-5-(perfluoroalkyl)pyrrole compounds from N-[1-chloro-1-(perfluoroalkyl)methyl]arylimidoyl chloride compounds | American Cyanamid Company (US) | 2000-09-13 | — | — | EP | disclosed |
| US-6034273-A | INSECTICIDES; MITICIDES | AMERICAN CYANAMID COMPANY (US) | 2000-03-07 | — | — | US | disclosed |
| CN-1238330-A | Process for preparation of 2-aryl-5-(perfluoroalkyl) pyrrole compounds | AMERICAN CYANAMID CO (US) | 1999-12-15 | — | — | CN | disclosed |
| EP-0934929-A1 | Process for the preparation of 2-aryl-5-(perfluoroalkyl)pyrrole compounds from N-(arylmethylene)-1-chloro-1-(perfluoroalkyl) methylamine compounds | American Cyanamid Company (US) | 1999-08-11 | — | — | EP | disclosed |
| EP-0347488-A1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1989-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049338-A1 | Process for the preparation of 2-aryl-5- (perfluoro-alkyl) pyrrole compounds from N-[1-chloro-1-(perfluoroalkyl) methyl] arylimidoyl chloride compounds | AFF1, AFF4, AFF2 | KIF11 439/4885ALDH1A1 1639/4885MAPT 4244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.