Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 9/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27633703 | 0.85 | KDM4E (0.44) | CYP11B1CYP11B2ARERBB2KIF11 | |
| SCHEMBL6561277 | 0.85 | KIF11 (0.49) | CYP11B1CYP11B2ARKIF11 | |
| SCHEMBL9390186 | 0.84 | AR (0.54) | ARKIF11PGR | |
| SCHEMBL10590631 | 0.84 | AR (0.54) | CYP11B1CYP11B2ARMAOAMAOB | |
| SCHEMBL3893100 | 0.84 | KDM4E (0.46) | ARMAOAMAOBERBB2 | |
| SCHEMBL9193868 | 0.83 | MAOA (0.45) | ARMAOAMAOBPGR | |
| Bromide SCHEMBL29618239 | 0.83 | KDM4E (0.45) | ARMAOAMAOBERBB2 | |
| SCHEMBL3893630 | 0.80 | AR (0.40) | CYP11B2ARMAOAMAOB | |
| SCHEMBL3896879 | 0.79 | KDM4E (0.35) | CYP11B1CYP11B2ARMAOAMAOB | |
| SCHEMBL7765241 | 0.78 | VCAM1 (0.43) | RAD51KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934930-B1 | Process for the preparation of 2-aryl-5-(perfluoroalkyl)pyrrole compounds from N-(perfluoroalkylmethyl)arylimidoyl chloride compounds | BASF SE (DE) | 2009-01-28 | — | — | EP | disclosed |
| EP-1035113-B1 | Process for the preparation of 2-aryl-5-(perfluoroalkyl)pyrrole compounds from N-[1-chloro-1-(perfluoroalkyl)methyl]arylimidoyl chloride compounds | BASF AG (DE) | 2004-10-06 | — | — | EP | disclosed |
| US-6596902-B2 | Useful for insecticides and the control of acarid pests; chemical intermediates in the preparation of arylpyrrole compounds such as chlorfenapyr | BASF AKTIENGESELLSCHAFT (DE) | 2003-07-22 | — | — | US | disclosed |
| US-20020049338-A1 | Process for the preparation of 2-aryl-5- (perfluoro-alkyl) pyrrole compounds from N-[1-chloro-1-(perfluoroalkyl) methyl] arylimidoyl chloride compounds | AMERICAN CYANAMID COMPANY | 2002-04-25 | — | — | US | disclosed |
| US-6320059-B1 | REACTING N-(1-CHLORO-1-(PERFLUOROALKYL)METHYL)ARYLIMIDOYL CHLORIDE COMPOUND WITH DIENEOPHILE COMPOUND OR SUBSTITUTED HALOETHANE COMPOUND, AND BASE, IN PRESENCE OF SOLVENT | AMERICAN CYANAMID COMPANY | 2001-11-20 | — | — | US | disclosed |
| EP-1035113-A2 | Process for the preparation of 2-aryl-5-(perfluoroalkyl)pyrrole compounds from N-[1-chloro-1-(perfluoroalkyl)methyl]arylimidoyl chloride compounds | American Cyanamid Company (US) | 2000-09-13 | — | — | EP | disclosed |
| US-6011161-A | Process for the preparation of 2-aryl-5-(perfluoroalkyl)pyrrole compounds from N-(perfluoro-alkylmethyl)arylimidoyl chloride compounds | AMERICAN CYANAMID COMPANY (US) | 2000-01-04 | — | — | US | disclosed |
| US-5965773-A | A CHEMICAL INTERMEDIATE FOR FORMING A PESTICIDE TO CONTROL INSECT AND ACARID PESTS | AMERICAN CYANAMID COMPANY (US) | 1999-10-12 | — | — | US | disclosed |
| CN-1230539-A | Process for preparation of 2-aryl-5-(perfluoroalkyl) pyrrole compounds from N-(perfluoroalkyl-methyl) arylimidoyl chloride compounds | AMERICAN CYANAMID CO (US) | 1999-10-06 | — | — | CN | disclosed |
| EP-0934930-A1 | Process for the preparation of 2-aryl-5-(perfluoroalkyl)pyrrole compounds from N-(perfluoroalkylmethyl)arylimidoyl chloride compounds | American Cyanamid Company (US) | 1999-08-11 | — | — | EP | disclosed |
| US-5817834-A | FROM (PERFLUOROALKYLMETHYL)ARYLIMIDOLYL CHLORIDE COMPOUNDS;INSECTICIDES, MITICIDES | AMERICAN CYANAMID COMPANY (US) | 1998-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049338-A1 | Process for the preparation of 2-aryl-5- (perfluoro-alkyl) pyrrole compounds from N-[1-chloro-1-(perfluoroalkyl) methyl] arylimidoyl chloride compounds | AFF1, AFF4, AFF2 | PTGES 4065/4885CYP11B1 1300/4885CYP11B2 1683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.