Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 6/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561450 | 0.76 | HTR7 (0.50) | ADORA1AVPR2AVPR1AMAPTTSHR | |
| SCHEMBL6561418 | 0.73 | BRD4 (0.49) | ADORA1NR1H3NPC1RAB9AADORA3 | |
| SCHEMBL14118409 | 0.72 | ALDH1A1 (0.50) | ADORA1NR1H3NR1H2NPC1RAB9A | |
| SCHEMBL6559724 | 0.70 | GAA (0.47) | ADORA1NR1H3NR1H2NPC1RAB9A | |
| SCHEMBL14007393 | 0.67 | NPC1 (0.52) | NR1H3NR1H2NPC1RAB9AAVPR1A | |
| SCHEMBL14210107 | 0.62 | NPC1 (0.45) | NR1H3NR1H2NPC1RAB9AAVPR1A | |
| SCHEMBL18952840 | 0.61 | NR1H3 (0.48) | NR1H3NR1H2NPC1RAB9ATP53 | |
| SCHEMBL16202035 | 0.61 | NR1H3 (0.71) | NR1H3NR1H2NPC1RAB9AMAPT | |
| SCHEMBL16642051 | 0.59 | TDP2 (0.43) | RAB9AHSD17B10MAPTTSHRSMN1; SMN2 | |
| SCHEMBL711569 | 0.59 | NPC1 (0.41) | NR1H3NR1H2NPC1RAB9AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071670-A1 | NOVEL DIPHENYL-SUBSTITUTED 5-RING-HETEROCYCLES, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM KG (DE) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999054314-A1 | NOVEL DIPHENYL-SUBSTITUTED 5-RING-HETEROCYCLES, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-10-28 | — | — | WO | disclosed |