SCHEMBL6561523

SCHEMBL6561523

C1=C2CCC3=Cc4cc5ccccc5cc4C3CCC2c2cc3ccccc3cc21

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.32
SLC6A2 P23975 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
SLC6A4 P31645 1/20 0.31
HTR7 P34969 1/20 0.31
HTR2B P41595 1/20 0.31
HTR3A P46098 1/20 0.31
SLC6A3 Q01959 1/20 0.31
HTR4 Q13639 1/20 0.31
BCHE P06276 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6560462 0.93 SLC6A2 (0.31) SLC6A2HTR2AHTR2CSLC6A4HTR7
SCHEMBL577658 0.76 KDM1A (0.39) KDM1A
Hydrochloric Acid SCHEMBL6858964 0.75 KDM1A (0.30) KDM1A
SCHEMBL775690 0.68 KDM1A (0.35) KDM1A
SCHEMBL3248949 0.68 KDM1A (0.35) KDM1A
SCHEMBL6561593 0.67 KDM1A (0.34) KDM1A
SCHEMBL1664601 0.66 ADRA2A (0.40)
SCHEMBL5845510 0.65 TLR4 (0.35) KDM1A
SCHEMBL7696567 0.64 KDM1A (0.32) KDM1AHTR2A
SCHEMBL29564576 0.64 SNCA (0.42) KDM1AHTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0818458-B1 TRANSITION METAL COMPOUND, POLYMERIZATION CATALYST FOR OLEFINS, AND PROCESS FOR PRODUCING OLEFINIC POLYMERS IDEMITSU KOSAN CO (JP) 2004-02-25 EP disclosed
US-6339135-B1 AS POLYMERIZATION CATALYST IDEMITSU KOSAN CO., LTD. (JP) 2002-01-15 US disclosed
EP-0818458-A1 TRANSITION METAL COMPOUND, POLYMERIZATION CATALYST FOR OLEFINS, AND PROCESS FOR PRODUCING OLEFINIC POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-01-14 EP disclosed