Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 3/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565533 | 0.92 | ACACB (0.45) | HSD11B1ACACBPTPN11ABL1RIN1 | |
| SCHEMBL6565339 | 0.91 | HPGD (0.39) | HSD11B1ACACBPTPN11ABL1RIN1 | |
| SCHEMBL6563328 | 0.89 | ACACB (0.36) | HSD11B1ACACBPTPN11ABL1RIN1 | |
| SCHEMBL7674981 | 0.89 | ABL1 (0.43) | ACACBPTPN11ABL1RIN1CNR2 | |
| SCHEMBL7686729 | 0.87 | PTPN11 (0.43) | ACACBPTPN11ABL1RIN1CNR2 | |
| SCHEMBL6565093 | 0.86 | ACACB (0.35) | ACACBPTPN11ABL1RIN1CNR2 | |
| SCHEMBL6561973 | 0.85 | JAK1 (0.38) | ACACBPTPN11JAK2 | |
| SCHEMBL6563912 | 0.85 | ACACB (0.34) | ACACBPTPN11ABL1RIN1CNR2 | |
| SCHEMBL6565336 | 0.85 | ACACB (0.34) | HSD11B1ACACBPTPN11ABL1RIN1 | |
| SCHEMBL6561938 | 0.84 | ABL1 (0.36) | ACACBABL1RIN1CNR2DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |