Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563672 | 0.87 | ACACB (0.38) | ACACBHPGDL3MBTL1KDM4EKMT2A | |
| SCHEMBL6565533 | 0.87 | ACACB (0.45) | ACACBJAK1PTPN11KMT2AALDH1A1 | |
| SCHEMBL6565339 | 0.85 | HPGD (0.39) | ACACBHPGDL3MBTL1PTPN11KMT2A | |
| SCHEMBL6565093 | 0.85 | ACACB (0.35) | ACACBHPGDL3MBTL1JAK1PTPN11 | |
| SCHEMBL6561810 | 0.85 | HSD11B1 (0.40) | ACACBPTPN11ALDH1A1ABL1RIN1 | |
| SCHEMBL6563912 | 0.84 | ACACB (0.34) | ACACBHPGDL3MBTL1JAK1PTPN11 | |
| SCHEMBL7675013 | 0.83 | ACACB (0.34) | ACACBJAK1PTPN11ALDH1A1MAPT | |
| SCHEMBL6563328 | 0.83 | ACACB (0.36) | ACACBJAK1PTPN11KMT2AALDH1A1 | |
| SCHEMBL6561934 | 0.82 | ACACB (0.33) | ACACBJAK1PTPN11KDM4EALDH1A1 | |
| SCHEMBL7674981 | 0.82 | ABL1 (0.43) | ACACBHPGDL3MBTL1PTPN11KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |