Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | SPIN1 | Q9Y657 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565533 | 0.90 | ACACB (0.45) | ACACBPTPN11ABL1RIN1CNR2 | |
| SCHEMBL6561810 | 0.89 | HSD11B1 (0.40) | ACACBPTPN11ABL1RIN1CNR2 | |
| SCHEMBL6565339 | 0.89 | HPGD (0.39) | ACACBPTPN11ABL1RIN1CNR2 | |
| SCHEMBL7674981 | 0.86 | ABL1 (0.43) | ACACBPTPN11ABL1RIN1CNR2 | |
| SCHEMBL7686729 | 0.84 | PTPN11 (0.43) | ACACBPTPN11ABL1RIN1CNR2 | |
| SCHEMBL6565093 | 0.84 | ACACB (0.35) | ACACBPTPN11ABL1RIN1CNR2 | |
| SCHEMBL6563597 | 0.84 | F10 (0.38) | ACACBF10 | |
| SCHEMBL6561973 | 0.83 | JAK1 (0.38) | ACACBPTPN11JAK1KMT2A | |
| SCHEMBL6563912 | 0.83 | ACACB (0.34) | ACACBPTPN11ABL1RIN1CNR2 | |
| SCHEMBL6565336 | 0.83 | ACACB (0.34) | ACACBPTPN11ABL1RIN1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |