Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11497223 | 0.78 | FAAH (0.52) | MAPTLMNAUSP2SLC6A2BLM | |
| SCHEMBL8227251 | 0.75 | MAPT (0.46) | MAPTABCC4ALDH1A1LMNAUSP2 | |
| SCHEMBL6559575 | 0.73 | PLA2G2C (0.42) | MAPTABCC4ALDH1A1LMNADDAH1 | |
| SCHEMBL8227704 | 0.71 | MAPT (0.42) | MAPTABCC4ALDH1A1LMNAUSP2 | |
| Carbamic Acid SCHEMBL8213815 | 0.71 | MAPT (0.42) | MAPTABCC4ALDH1A1LMNADDAH1 | |
| Carbamic Acid SCHEMBL8216451 | 0.71 | MAPT (0.42) | MAPTABCC4ALDH1A1LMNADDAH1 | |
| SCHEMBL11438610 | 0.70 | TSHR (0.50) | MAPTABCC4LMNAUSP2BLM | |
| SCHEMBL32689516 | 0.68 | FAAH (0.56) | MAPTABCC4ALDH1A1LMNAUSP2 | |
| SCHEMBL5859613 | 0.68 | MAPT (0.48) | MAPTABCC4ALDH1A1LMNADDAH1 | |
| SCHEMBL2805648 | 0.67 | MAPT (0.43) | MAPTABCC4ALDH1A1LMNADDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6756500-B1 | SUBJECTING SUBSTITUTED ALPHA, OMEGA-DIENE IN PRESENCE OF RUTHENIUM, OSMIUM OR MOLYBDENUM HOMOGENEOUS OR HETEROGENEOUS CATALYST TO METATHESIS REACTION IN PRESENCE OF IONIC LIQUID TO FORM CYCLIC COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 2004-06-29 | — | — | US | disclosed |
| EP-0990641-B1 | Process for the synthesis of alpha-substituted ring systems | BAYER CHEMICALS AG (DE) | 2004-03-17 | — | — | EP | disclosed |
| EP-1035093-B1 | Metathesis in the presence of ionic liquids | BAYER AG (DE) | 2003-09-10 | — | — | EP | disclosed |
| US-6235925-B1 | RING CLOSURE METHATHESIS AND NOBLE METAL CATALYSTS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-05-22 | — | — | US | disclosed |
| EP-1035093-A2 | Metathesis in the presence of ionic liquids | BAYER AG (DE) | 2000-09-13 | — | — | EP | disclosed |
| EP-0990641-A1 | Process for the synthesis of alpha-substituted ring systems | Bayer Aktiengesellschaft (DE) | 2000-04-05 | — | — | EP | disclosed |