Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL8213815 | 1.00 | MAPT (0.42) | MAPTABCC4ALDH1A1LMNADDAH1 | |
| SCHEMBL4612120 | 0.78 | GPR84 (0.44) | MAPT | |
| SCHEMBL30599528 | 0.75 | MAPT (0.46) | MAPTABCC4ALDH1A1LMNAUSP2 | |
| SCHEMBL7535185 | 0.73 | DDAH1 (0.31) | ALDH1A1DDAH1 | |
| SCHEMBL6559575 | 0.73 | PLA2G2C (0.42) | MAPTABCC4ALDH1A1LMNADDAH1 | |
| SCHEMBL11290897 | 0.72 | — | — | |
| SCHEMBL6562004 | 0.71 | MAPT (0.46) | MAPTABCC4ALDH1A1LMNADDAH1 | |
| SCHEMBL15487288 | 0.71 | SLC6A2 (0.33) | ALDH1A1SMN1; SMN2TSHRITGB3ITGA2B | |
| SCHEMBL27773776 | 0.70 | ALDH1A1 (0.43) | MAPTABCC4ALDH1A1LMNAUSP2 | |
| Urea SCHEMBL3773480 | 0.70 | MAPT (0.61) | MAPTABCC4ALDH1A1LMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166236-A | Vinyl carbonate and vinyl carbamate contact lens material monomers | BAUSCH & LOMB INCORPORATED (US) | 2000-12-26 | — | — | US | disclosed |
| EP-0757033-B1 | Vinyl carbonate and vinyl carbamate monomers for a contact lens material | BAUSCH & LOMB (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0396364-B1 | Copolymers of vinyl carbonate and vinyl carbamate as contact lens material | BAUSCH & LOMB (US) | 1997-06-11 | — | — | EP | disclosed |
| US-5610252-A | Vinyl carbonate and vinyl carbamate contact lens material monomers | BAUSCH & LOMB INCORPORATED (US) | 1997-03-11 | — | — | US | disclosed |
| EP-0757033-A2 | Vinyl carbonate and vinyl carbamate monomers for a contact lens material | BAUSCH & LOMB INCORPORATED (US) | 1997-02-05 | — | — | EP | disclosed |
| US-5070215-A | Gas permeable contact lenses | BAUSCH & LOMB INCORPORATED (US) | 1991-12-03 | — | — | US | disclosed |
| EP-0396364-A2 | Novel vinyl carbonate and vinyl carbamate contact lens material monomers | BAUSCH & LOMB INCORPORATED (US) | 1990-11-07 | — | — | EP | disclosed |