Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2060780 | 0.86 | ALDH1A1 (0.53) | GPR35TDP1ALDH1A1TSHRHPGD | |
| SCHEMBL6677996 | 0.81 | GAA (0.57) | GPR35TDP1ALDH1A1TSHRHPGD | |
| SCHEMBL10913298 | 0.79 | HSD17B10 (0.56) | TDP1ALDH1A1HPGDSMN1; SMN2MAPK1 | |
| SCHEMBL7838979 | 0.79 | ALDH1A1 (0.55) | TDP1ALDH1A1TSHRSMN1; SMN2GAA | |
| SCHEMBL7740419 | 0.79 | ALDH1A1 (0.61) | TDP1ALDH1A1SMN1; SMN2TP53GAA | |
| SCHEMBL7740425 | 0.79 | TDP1 (0.47) | TDP1ALDH1A1TSHRHPGDSMN1; SMN2 | |
| SCHEMBL29895481 | 0.78 | RECQL (0.59) | GPR35TDP1ALDH1A1HPGDMEN1 | |
| SCHEMBL4620082 | 0.78 | RECQL (0.59) | GPR35TDP1ALDH1A1HPGDMEN1 | |
| SCHEMBL27708625 | 0.77 | GRIK1 (0.51) | GPR35TDP1ALDH1A1TSHRHPGD | |
| SCHEMBL1744862 | 0.76 | ALDH1A1 (0.53) | TDP1ALDH1A1TSHRMAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304994-B1 | PYRROLYL-SUBSTITUTED NITROPHENOLS USED AS DIRECT COLORANTS | HENKEL KGAA (DE) | 2004-10-20 | — | — | EP | claimed |
| EP-1304994-A1 | PYRROLYL-SUBSTITUTED NITROPHENOLS USED AS DIRECT COLORANTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-05-02 | — | — | EP | claimed |
| WO-2002009661-A1 | PYRROLYL-SUBSTITUTED NITROPHENOLS USED AS DIRECT COLORANTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-02-07 | — | — | WO | claimed |
| EP-1304994-B1 | PYRROLYL-SUBSTITUTED NITROPHENOLS USED AS DIRECT COLORANTS | HENKEL KGAA (DE) | 2004-10-20 | — | — | EP | disclosed |
| EP-1304994-A1 | PYRROLYL-SUBSTITUTED NITROPHENOLS USED AS DIRECT COLORANTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002009661-A1 | PYRROLYL-SUBSTITUTED NITROPHENOLS USED AS DIRECT COLORANTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-02-07 | — | — | WO | disclosed |
| EP-1054889-A1 | NEW OXAZOLIDINONES WITH AZOL-CONTAINING TRICYCLES | Bayer Aktiengesellschaft (DE) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999040094-A1 | AGENT FOR SEALING METALLIC GROUND COATS, ESPECIALLY GROUND COATS CONSISTING OF ZINC OR ZINC ALLOYS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-08-12 | — | — | WO | disclosed |
| US-4617316-A | Insecticidal heteroaryl substituted phenyl benzoylureas | FMC CORPORATION (US) | 1986-10-14 | — | — | US | disclosed |