Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 16/20 | 0.50 |
| ▸ | METAP1 | P53582 | 8/20 | 0.50 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935836 | 0.83 | METAP2 (0.46) | METAP2METAP1DPEP1NPC1RAB9A | |
| SCHEMBL6565227 | 0.82 | METAP2 (0.50) | METAP2METAP1 | |
| SCHEMBL6934858 | 0.79 | METAP2 (0.46) | METAP2METAP1NPC1RAB9AKMT2A | |
| SCHEMBL6940184 | 0.79 | METAP2 (0.49) | METAP2METAP1NPC1RAB9A | |
| SCHEMBL7353275 | 0.76 | METAP2 (0.60) | METAP2METAP1NPC1RAB9AKMT2A | |
| SCHEMBL11522879 | 0.74 | KMT2A (0.51) | DPEP1NPC1RAB9AKMT2AHDAC3 | |
| SCHEMBL7351848 | 0.74 | METAP2 (0.69) | METAP2METAP1NPC1RAB9A | |
| SCHEMBL6484511 | 0.74 | METAP2 (0.78) | METAP2METAP1NPC1RAB9AKMT2A | |
| SCHEMBL6938170 | 0.74 | METAP2 (0.49) | METAP2METAP1KMT2A | |
| Hydrochloric Acid SCHEMBL7353393 | 0.73 | METAP2 (0.67) | METAP2METAP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-B1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LAB (US) | 2004-10-27 | — | — | EP | claimed |