Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 6/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4890987 | 0.80 | EPHX2 (0.40) | RAB9AMAPTESRRGNPC1 | |
| SCHEMBL4889952 | 0.71 | TRPV1 (0.49) | — | |
| SCHEMBL6562709 | 0.68 | TRPV1 (0.60) | — | |
| SCHEMBL4886449 | 0.67 | ALDH1A1 (0.44) | MAPTNAMPT | |
| SCHEMBL4880046 | 0.65 | LMNA (0.53) | MAPT | |
| SCHEMBL10402495 | 0.64 | ALDH1A1 (0.41) | RAB9AMAPTNPC1 | |
| SCHEMBL10402494 | 0.64 | ALDH1A1 (0.41) | RAB9AMAPTNPC1 | |
| SCHEMBL12049778 | 0.62 | EPHX2 (0.40) | RAB9AESRRGNPC1 | |
| SCHEMBL9428588 | 0.62 | EPHX2 (0.54) | RAB9ANPC1 | |
| SCHEMBL4391756 | 0.61 | RAB9A (0.49) | RAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303483-A4 | NOVEL THIOUREA DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | PACIFIC CORP (KR) | 2004-11-03 | — | — | EP | disclosed |
| EP-1303483-A1 | NOVEL THIOUREA DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | PACIFIC CORPORATION (KR) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002016318-A1 | NOVEL THIOUREA DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | PACIFIC CORPORATION (KR) | 2002-02-28 | — | — | WO | disclosed |