Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.39 |
| ▸ | PPARA | Q07869 | 7/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563256 | 0.81 | HPGD (0.45) | HPGDADRA2CMAOAADRA1ADRD3 | |
| SCHEMBL7673754 | 0.81 | NQO2 (0.41) | HPGDADRA2CMAOAADRA1ADRD3 | |
| SCHEMBL6563729 | 0.80 | PPARG (0.41) | PPARGPPARAPPARDPTPN11PTPRB | |
| SCHEMBL6563355 | 0.78 | PTPN11 (0.47) | PPARGPPARAPPARDPTPN11CTSK | |
| SCHEMBL6565434 | 0.77 | PTPN11 (0.41) | PPARGPPARAPPARDPTPN11KMT2A | |
| SCHEMBL6563676 | 0.76 | NAMPT (0.42) | PPARGPPARAPPARDPTPN11CYP3A4 | |
| SCHEMBL6563070 | 0.76 | PTPN11 (0.44) | PPARGPPARAPPARDPTPN11KMT2A | |
| SCHEMBL7158402 | 0.74 | PPARG (0.47) | PPARGPPARAPPARDKMT2AALDH1A1 | |
| SCHEMBL6563323 | 0.73 | MAPT (0.38) | PPARGPPARAPPARDPTPN11MAPT | |
| SCHEMBL6563283 | 0.73 | PTPN11 (0.46) | PTPN11HPGDALDH1A1MAPTPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |