Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.39 |
| ▸ | F2 | P00734 | 3/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.38 |
| ▸ | TMPRSS6 | Q8IU80 | 3/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563256 | 0.89 | HPGD (0.45) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL6563625 | 0.82 | PRSS1 (0.43) | HPGDALDH1A1PRSS1F2PRSS2 | |
| SCHEMBL6563536 | 0.81 | PPARG (0.39) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7804850 | 0.79 | RAB9A (0.36) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL6561914 | 0.76 | GRM5 (0.43) | HPGDALDH1A1PRSS1F2PRSS2 | |
| SCHEMBL7678092 | 0.76 | F2 (0.40) | HPGDALDH1A1PRSS1F2PRSS2 | |
| SCHEMBL7669697 | 0.76 | MAPK13 (0.40) | HPGDALDH1A1PRSS1F2PRSS2 | |
| SCHEMBL7670097 | 0.76 | HPGD (0.45) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL6563277 | 0.76 | F2 (0.41) | PRSS1F2MRGPRX1 | |
| SCHEMBL6565256 | 0.75 | AKR1C3 (0.44) | ALDH1A1PRSS1F2PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |