Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563070 | 0.90 | PTPN11 (0.44) | NAMPTPTPN11PPARGPPARAPPARD | |
| SCHEMBL6563729 | 0.83 | PPARG (0.41) | PTPN11PPARGPPARAPPARD | |
| SCHEMBL7676492 | 0.81 | CCNA2 (0.41) | NAMPTRAB9AGALR3TDP1ALDH1A1 | |
| SCHEMBL6565434 | 0.81 | PTPN11 (0.41) | PTPN11PPARGPPARAPPARDKMT2A | |
| SCHEMBL6563355 | 0.80 | PTPN11 (0.47) | PTPN11PPARGPPARAPPARDCYP17A1 | |
| SCHEMBL6563589 | 0.80 | GALR3 (0.50) | NAMPTRAB9AGALR3TDP1ALDH1A1 | |
| SCHEMBL6563283 | 0.80 | PTPN11 (0.46) | PTPN11CYP17A1ALDH1A1 | |
| SCHEMBL7686729 | 0.77 | PTPN11 (0.43) | NAMPTPTPN11ALDH1A1KMT2A | |
| SCHEMBL7674981 | 0.77 | ABL1 (0.43) | NAMPTPTPN11RAB9AALDH1A1KMT2A | |
| SCHEMBL6563536 | 0.76 | PPARG (0.39) | PTPN11PPARGPPARAPPARDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |