Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 9/20 | 0.42 |
| ▸ | LDHB | P07195 | 9/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 2/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.35 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563630 | 0.88 | LMNA (0.37) | LDHALDHBHTTALDH1A1LMNA | |
| SCHEMBL6562338 | 0.87 | GAA (0.47) | LDHALDHBHTTALDH1A1LMNA | |
| SCHEMBL7677130 | 0.81 | PRSS1 (0.41) | KMT2AKLK1KLK5PRSS1F2 | |
| SCHEMBL7670696 | 0.79 | KMT2A (0.44) | KMT2AKLK1KLK5PRSS1SMN1; SMN2 | |
| SCHEMBL7670899 | 0.79 | PRSS1 (0.43) | ALDH1A1LMNAPRSS1F2PRSS2 | |
| SCHEMBL6563625 | 0.79 | PRSS1 (0.43) | ALDH1A1LMNAPRSS1F2PRSS2 | |
| SCHEMBL7678064 | 0.78 | KLK1 (0.49) | KLK1KLK5PRSS1F2PRSS2 | |
| SCHEMBL7674188 | 0.78 | EGLN1 (0.44) | LMNAKLK1KLK5PRSS1F2 | |
| SCHEMBL7676492 | 0.77 | CCNA2 (0.41) | ALDH1A1MAPTPRSS1SMN1; SMN2F2 | |
| SCHEMBL6565363 | 0.75 | GAA (0.41) | LDHALDHBHTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |