Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 9/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.40 |
| ▸ | TMPRSS6 | Q8IU80 | 3/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7670899 | 0.88 | PRSS1 (0.43) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL6563625 | 0.88 | PRSS1 (0.43) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL7676492 | 0.88 | CCNA2 (0.41) | PRSS1NPSR1F2PRSS2PRSS3 | |
| SCHEMBL7674188 | 0.86 | EGLN1 (0.44) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL6563325 | 0.85 | KMT2A (0.50) | KMT2ANPSR1MEN1 | |
| SCHEMBL7670696 | 0.83 | KMT2A (0.44) | PRSS1KMT2AF2PRSS2PRSS3 | |
| SCHEMBL7678064 | 0.82 | KLK1 (0.49) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL7670097 | 0.81 | HPGD (0.45) | PRSS1KMT2AF2PRSS2PRSS3 | |
| SCHEMBL6563773 | 0.81 | LDHA (0.42) | PRSS1KMT2AF2PRSS2PRSS3 | |
| SCHEMBL7675043 | 0.81 | F7 (0.42) | PRSS1F2PRSS2PRSS3TMPRSS6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |