Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LDHA | P00338 | 9/20 | 0.43 |
| ▸ | LDHB | P07195 | 9/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563773 | 0.87 | LDHA (0.42) | GAALDHALDHBHTTALDH1A1 | |
| SCHEMBL6565363 | 0.87 | GAA (0.41) | GAALDHALDHBMYCHTT | |
| SCHEMBL28865452 | 0.85 | GAA (0.56) | GAALDHALDHBMYCHTT | |
| SCHEMBL6565441 | 0.78 | KMT2A (0.46) | HTTALDH1A1MAPTKMT2AVNN1 | |
| SCHEMBL6565480 | 0.78 | GSK3B (0.47) | ALDH1A1LMNAVNN1SMN1; SMN2 | |
| SCHEMBL6563532 | 0.78 | ALDH1A1 (0.44) | HTTALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL6565285 | 0.77 | NPC1 (0.49) | ALDH1A1MAPTVNN1 | |
| SCHEMBL6563630 | 0.76 | LMNA (0.37) | GAALDHALDHBMYCHTT | |
| SCHEMBL6563651 | 0.73 | MAPK13 (0.45) | GAAHTTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6563777 | 0.73 | GSK3B (0.45) | ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |