Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565371 | 0.94 | KCNK3 (0.34) | KCNK3MEN1KMT2ARAB9AGABRA1 | |
| SCHEMBL7676439 | 0.92 | HSD11B1 (0.32) | KCNK3MEN1KMT2AITGB3ITGA2B | |
| SCHEMBL6565417 | 0.87 | PTPN11 (0.36) | KCNK3PTPN11HSD11B1GAA | |
| SCHEMBL6561984 | 0.86 | MEN1 (0.40) | KCNK3MEN1KMT2ARAB9AGABRA1 | |
| SCHEMBL6563725 | 0.86 | GAA (0.33) | MEN1KMT2APTPN11GAASMN1; SMN2 | |
| SCHEMBL6565533 | 0.83 | ACACB (0.45) | MEN1KMT2ARAB9APTPN11HSD11B1 | |
| SCHEMBL6561843 | 0.83 | GAA (0.31) | MEN1KMT2AITGB3ITGA2BPTPN11 | |
| SCHEMBL6563511 | 0.82 | PTPN11 (0.40) | PTPN11HSD11B1 | |
| SCHEMBL6563364 | 0.81 | ITGB3 (0.36) | KCNK3MEN1KMT2ARAB9AGABRA1 | |
| SCHEMBL6565215 | 0.81 | PIK3CA (0.38) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |