Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565283 | 1.00 | HSD11B1 (0.38) | HSD11B1L3MBTL1NPSR1NAAAOPRM1 | |
| SCHEMBL162237 | 0.82 | L3MBTL1 (0.41) | HSD11B1L3MBTL1NPSR1OPRM1PKM | |
| SCHEMBL2968353 | 0.82 | L3MBTL1 (0.41) | HSD11B1L3MBTL1NPSR1OPRM1PKM | |
| SCHEMBL997079 | 0.82 | L3MBTL1 (0.41) | HSD11B1L3MBTL1NPSR1OPRM1PKM | |
| SCHEMBL19260910 | 0.72 | OPRM1 (0.45) | HSD11B1L3MBTL1OPRM1PKM | |
| Formic Acid SCHEMBL27903276 | 0.72 | L3MBTL1 (0.47) | HSD11B1L3MBTL1OPRM1PKM | |
| SCHEMBL3640549 | 0.71 | AOC3 (0.47) | L3MBTL1 | |
| SCHEMBL30722353 | 0.71 | HSD11B1 (0.39) | HSD11B1L3MBTL1OPRM1PKMALDH1A1 | |
| SCHEMBL26966058 | 0.71 | HSD11B1 (0.39) | HSD11B1L3MBTL1OPRM1PKMALDH1A1 | |
| SCHEMBL5968911 | 0.71 | L3MBTL1 (0.37) | L3MBTL1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448520-A1 | BENZAMIDE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND THEIR PHARMACEUTICAL USE | SMITHKLINE BEECHAM PLC (GB) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003045913-A1 | BENZAMIDE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND THEIR PHARMACEUTICAL USE | SMITHKLINE BEECHAM P.L.C. (GB) | 2003-06-05 | — | — | WO | disclosed |