Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565093 | 0.91 | ACACB (0.35) | ACACBITGB3ITGA2BJAK1RAB9A | |
| SCHEMBL6563912 | 0.90 | ACACB (0.34) | ACACBITGB3ITGA2BJAK1RAB9A | |
| SCHEMBL6561934 | 0.88 | ACACB (0.33) | ACACBITGB3ITGA2BJAK1RAB9A | |
| SCHEMBL6563668 | 0.87 | TPSAB1 (0.38) | ACACBITGB3ITGA2BRAB9ANPC1 | |
| SCHEMBL6565533 | 0.86 | ACACB (0.45) | ACACBJAK1RAB9APTPN11DDB1 | |
| SCHEMBL6561810 | 0.83 | HSD11B1 (0.40) | ACACBRAB9APTPN11DDB1CRBN | |
| SCHEMBL6565336 | 0.83 | ACACB (0.34) | ACACBJAK1RAB9APTPN11ABL1 | |
| SCHEMBL6565339 | 0.83 | HPGD (0.39) | ACACBRAB9APTPN11ABL1RIN1 | |
| SCHEMBL7676439 | 0.81 | HSD11B1 (0.32) | ITGB3ITGA2BPTPN11DDB1CRBN | |
| SCHEMBL6563328 | 0.81 | ACACB (0.36) | ACACBJAK1RAB9APTPN11DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |