Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 4/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563696 | 0.86 | HPGD (0.37) | HPGDKDM4EMEN1KMT2ATSHR | |
| SCHEMBL6565512 | 0.80 | GAA (0.40) | HPGDMEN1KMT2AHSD11B1ALDH1A1 | |
| SCHEMBL6565417 | 0.76 | PTPN11 (0.36) | HPGDKCNK3HSD11B1ALDH1A1GAA | |
| SCHEMBL6563266 | 0.74 | LRRK2 (0.42) | HPGDMEN1KMT2AHSD11B1ALDH1A1 | |
| SCHEMBL7806152 | 0.73 | HRH3 (0.37) | HSD11B1ALDH1A1GAA | |
| SCHEMBL6563261 | 0.72 | HSD11B1 (0.38) | HPGDHSD11B1ALDH1A1GAA | |
| SCHEMBL6563410 | 0.70 | GAA (0.40) | HPGDMEN1KMT2ATSHRHSD11B1 | |
| SCHEMBL5885749 | 0.70 | ACACB (0.48) | TSHRALDH1A1 | |
| SCHEMBL6563591 | 0.69 | LRRK2 (0.39) | HPGDMEN1KMT2AHSD11B1ALDH1A1 | |
| SCHEMBL6565356 | 0.69 | GAA (0.42) | HPGDMEN1KMT2AHSD11B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |