Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565512 | 0.89 | GAA (0.40) | HPGDMEN1KMT2AHSD11B1GAA | |
| SCHEMBL6565856 | 0.86 | IMPDH2 (0.38) | HPGDKDM4EMEN1KMT2ATSHR | |
| SCHEMBL6563261 | 0.80 | HSD11B1 (0.38) | HPGDMAPTHSD11B1GAAALDH1A1 | |
| SCHEMBL6565417 | 0.79 | PTPN11 (0.36) | HPGDHSD11B1GAAALDH1A1NAMPT | |
| SCHEMBL6561970 | 0.78 | GAA (0.49) | HPGDLMNAHSD11B1GAAALDH1A1 | |
| SCHEMBL6563266 | 0.78 | LRRK2 (0.42) | HPGDMEN1KMT2AHSD11B1GAA | |
| SCHEMBL6563410 | 0.77 | GAA (0.40) | HPGDMEN1KMT2ATSHRHSD11B1 | |
| SCHEMBL6565851 | 0.77 | F2 (0.37) | GAASMN1; SMN2 | |
| SCHEMBL6565424 | 0.77 | ITGB3 (0.42) | HSD11B1HCRTR1 | |
| SCHEMBL7806152 | 0.76 | HRH3 (0.37) | HSD11B1GAAALDH1A1L3MBTL1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |