Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL6566368

CCOC(=O)Oc1cccc2c([S+]3CCCC3)cccc12.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.38
ACHE P22303 2/20 0.33
ESR1 P03372 6/20 0.33
ESR2 Q92731 6/20 0.33
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
GAA P10253 3/20 0.33
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP14 P50281 1/20 0.31
ELANE P08246 1/20 0.31
CCR8 P51685 1/20 0.31
KDM4E B2RXH2 1/20 0.31
KCNH2 Q12809 6/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL645884 0.94 TYMS (0.38) TYMSMEN1KMT2AGAAALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL6566199 0.92 ELANE (0.36) TYMSACHEGAAALDH1A1SMN1; SMN2
Trifluoromethanesulfonic Acid SCHEMBL6564792 0.90 ELANE (0.44) ACHEKMT2ASMN1; SMN2ELANEKCNH2
Trifluoromethanesulfonic Acid SCHEMBL6566214 0.88 HSD17B10 (0.34) ACHEESR1ESR2MEN1KMT2A
Trifluoromethanesulfonic Acid SCHEMBL6564876 0.86 GAA (0.32) ESR1ESR2MEN1KMT2AGAA
Trifluoromethanesulfonic Acid SCHEMBL646751 0.86 MMP2 (0.33) TYMSMEN1KMT2AALDH1A1MMP2
Trifluoromethanesulfonic Acid SCHEMBL6564688 0.85 GAA (0.32) ESR1ESR2MEN1KMT2AGAA
Trifluoromethanesulfonic Acid SCHEMBL6563968 0.85 ALDH1A1 (0.39) ACHEMEN1KMT2AGAAALDH1A1
SCHEMBL3154705 0.84 TYMS (0.35) TYMSMEN1KMT2AGAAALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL645685 0.84 ELANE (0.40) ACHEELANEKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0849634-B1 Radiation sensitive resin composition JSR CORP (JP) 2004-03-31 EP disclosed
US-20010014427-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 2001-08-16 US disclosed
US-6187504-B1 PHOTOSENSITIVE BLEND CONTAINING A NAPHTHALENE SULFONIUM SULFONATE DERIVATIVE PHOTOACID GENERATOR, RESIN HAVING ALKALI INSOLUBLE GROUPS CLEAVABLE BY ACID, AN ALKALI SOLUBLE RESIN AND A SOLUBILITY CONTROL AGENT; POSITIVES, RESOLUTION JSR CORPORATION (JP) 2001-02-13 US disclosed
EP-0849634-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-06-24 EP disclosed