Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.48 |
| ▸ | ECE1 | P42892 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CD74 | P04233 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565718 | 0.88 | ALDH1A1 (0.51) | LOXL2ECE1TAAR1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL17261481 | 0.79 | TAAR1 (0.71) | LOXL2ECE1TAAR1ALDH1A1MAPT | |
| SCHEMBL6567252 | 0.79 | MAPT (0.52) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL6568646 | 0.79 | KDM4E (0.61) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL6565582 | 0.75 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL6568655 | 0.74 | CNR2 (0.50) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL6568589 | 0.74 | CNR2 (0.39) | LOXL2TAAR1ALDH1A1MAPTMEN1 | |
| SCHEMBL5778814 | 0.71 | LOXL2 (0.60) | LOXL2TAAR1ALDH1A1MAPTMEN1 | |
| SCHEMBL27827196 | 0.70 | KDM4E (0.49) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL27827226 | 0.69 | KDM4E (0.66) | ECE1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402887-A1 | New compounds for the inhibition of undesired cell proliferation and use thereof | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |
| EP-1402888-A1 | The use of substituted carbocyclic compounds as rotamases inhibitors | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |