Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 2/20 | 0.47 |
| ▸ | FNTB | P49356 | 2/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | GLS | O94925 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMO | Q99835 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6568615 | 0.80 | ROCK2 (0.54) | DHODHSMO | |
| SCHEMBL4347822 | 0.77 | KMT2A (0.68) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL10792361 | 0.76 | MEN1 (0.53) | MEN1KMT2AALDH1A1HPGDFNTA | |
| SCHEMBL6566906 | 0.75 | POLB (0.66) | MEN1KMT2AALDH1A1TACR1DHODH | |
| SCHEMBL4347446 | 0.75 | MAPT (0.66) | ALDH1A1HPGDMAPTHTT | |
| SCHEMBL6566816 | 0.73 | POLB (0.69) | MEN1KMT2AMAPT | |
| SCHEMBL6568657 | 0.73 | BCAT2 (0.50) | MEN1KMT2ATACR1 | |
| SCHEMBL5203197 | 0.73 | CNR1 (0.55) | MEN1KMT2AHPGDFNTAFNTB | |
| SCHEMBL4342381 | 0.73 | KMT2A (0.68) | MEN1KMT2ADHODHMAPTHTT | |
| SCHEMBL6567288 | 0.72 | HTT (0.55) | MEN1KMT2AALDH1A1DHODHMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402887-A1 | New compounds for the inhibition of undesired cell proliferation and use thereof | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |
| EP-1402888-A1 | The use of substituted carbocyclic compounds as rotamases inhibitors | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |