SCHEMBL6567759

SCHEMBL6567759

COc1c(C2CCCCC2)cc(CCO)cc1C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 2/20 0.36
NUDT1 P36639 1/20 0.36
BACE1 P56817 1/20 0.36
HTR2A P28223 2/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.34
POLB P06746 1/20 0.33
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA4 P22748 2/20 0.32
CA6 P23280 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
DHFR P00374 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
KCNH2 Q12809 1/20 0.32
FKBP1A P62942 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6567002 0.92 TNKS2 (0.40) ALDH1A1KDM4ENUDT1BACE1HTR2A
SCHEMBL7941423 0.85 ALDH1A1 (0.46) ALDH1A1MEN1KMT2ASIGMAR1FKBP1A
SCHEMBL7794935 0.85 THRA (0.46) ALDH1A1PTGDR2MEN1KMT2ASIGMAR1
SCHEMBL6567025 0.83 ALDH1A1 (0.42) ALDH1A1KDM4ENUDT1BACE1POLB
SCHEMBL6568807 0.83 ALDH1A1 (0.38) ALDH1A1KDM4ENUDT1BACE1HTR2A
SCHEMBL7786559 0.82 THRB (0.46) ALDH1A1PTGDR2TDP1
SCHEMBL6568830 0.81 ALDH1A1 (0.38) ALDH1A1KDM4ENUDT1BACE1HTR2A
SCHEMBL8430350 0.81 L3MBTL1 (0.43) ALDH1A1PTGDR2POLBMEN1KMT2A
SCHEMBL6567279 0.81 DHFR (0.43) ALDH1A1KDM4EHTR2ACA1CA2
SCHEMBL2916926 0.76 ALDH1A1 (0.40) ALDH1A1KDM4ENUDT1BACE1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1484334-A2 Process for producing phosphite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-08 EP disclosed
US-20040225145-A1 Process for producing phosphite SUMITOMO CHEMICAL COMPANY, LIMITED 2004-11-11 US disclosed
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040225145-A1 Process for producing phosphite PHOSPHO1, PLCG1, PLCG2 ALDH1A1 4488/4885KDM4E 2923/4885NUDT1 1593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.