Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6568071 | 0.86 | F10 (0.64) | ALDH1A1SMN1; SMN2POLBF10MEN1 | |
| SCHEMBL6387366 | 0.83 | F10 (0.52) | ALDH1A1SMN1; SMN2POLBF10CA12 | |
| SCHEMBL29259785 | 0.77 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2POLBCA12CA1 | |
| SCHEMBL29965415 | 0.72 | NPC1 (0.54) | ALDH1A1CA12CA1CA2CA5A | |
| SCHEMBL6565074 | 0.71 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2POLBF10CA1 | |
| SCHEMBL30014728 | 0.71 | HTR1A (0.42) | ALDH1A1ABCB1MEN1BCHEKMT2A | |
| SCHEMBL6392460 | 0.71 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2POLBF10CA12 | |
| SCHEMBL4136411 | 0.71 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2POLBCA12CA1 | |
| SCHEMBL10727095 | 0.70 | RXRA (0.64) | SMN1; SMN2POLB | |
| SCHEMBL10460467 | 0.70 | ALDH1A1 (0.77) | ALDH1A1SMN1; SMN2POLBCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1443041-A1 | 5-AMIDINO-2-HYDROXYBENZENESULFONAMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME, MEDICINAL USE THEREOF AND INTERMEDIATES IN THE PRODUCTION THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2004-08-04 | — | — | EP | disclosed |