Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 3/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | CPA1 | P15085 | 2/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6568255 | 1.00 | LMNA (0.46) | LMNATDP1POLBMMEOPRL1 | |
| SCHEMBL7224758 | 1.00 | LMNA (0.46) | LMNATDP1POLBMMEOPRL1 | |
| SCHEMBL6568332 | 0.87 | ITGA4 (0.47) | ITGA4 | |
| SCHEMBL7222897 | 0.80 | ACACB (0.43) | LMNAOPRL1NPSR1KMT2AL3MBTL1 | |
| SCHEMBL5652297 | 0.78 | OPRL1 (0.44) | OPRL1 | |
| SCHEMBL7838610 | 0.78 | OPRL1 (0.44) | OPRL1 | |
| SCHEMBL6569671 | 0.78 | OPRL1 (0.44) | OPRL1 | |
| SCHEMBL10510512 | 0.75 | CYP2D6 (0.47) | TDP1OPRL1ITGA4 | |
| SCHEMBL5651677 | 0.75 | CYP2D6 (0.47) | TDP1OPRL1ITGA4 | |
| SCHEMBL13534726 | 0.75 | CYP2D6 (0.47) | TDP1OPRL1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161416-B1 | ALPHA-AMINOACETIC ACID DERIVATIVES USEFUL AS ALPHA 4 BETA 7 - RECEPTOR ANTAGONISTS | ELAN PHARM INC (US) | 2004-04-14 | — | — | EP | claimed |