Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6568255 | 0.87 | LMNA (0.46) | ITGA4 | |
| SCHEMBL6568258 | 0.87 | LMNA (0.46) | ITGA4 | |
| SCHEMBL7224758 | 0.87 | LMNA (0.46) | ITGA4 | |
| SCHEMBL6568912 | 0.75 | ITGB1 (0.51) | ITGA4ITGB1 | |
| SCHEMBL7222897 | 0.73 | ACACB (0.43) | — | |
| SCHEMBL7401957 | 0.72 | ITGB1 (0.43) | ITGA4ITGB1 | |
| SCHEMBL5679669 | 0.72 | ITGB1 (0.63) | ITGA4ITGB1 | |
| SCHEMBL5681731 | 0.71 | ITGA4 (0.43) | ITGA4ITGB1 | |
| SCHEMBL13841280 | 0.70 | ITGB1 (0.57) | ITGA4ITGB1 | |
| SCHEMBL12834784 | 0.69 | ITGA4 (0.44) | ITGA4ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161416-B1 | ALPHA-AMINOACETIC ACID DERIVATIVES USEFUL AS ALPHA 4 BETA 7 - RECEPTOR ANTAGONISTS | ELAN PHARM INC (US) | 2004-04-14 | — | — | EP | claimed |
| US-6545160-B2 | Alpha-aminoacetic acid derivatives bind alpha 4 beta 7 integrin, useful for treatment of inflammatory diseases in mammalian patient, such as asthma, Alzheimer's disease, atherosclerosis, AIDS dementia, diabetes, rheumatoid arthritis | ELAN PHARMACEUTICALS, INC. | 2003-04-08 | — | — | US | disclosed |